INT226912

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL8) extracellular space (IL8) transport (Slc11a1)
extracellular region (IL8) intracellular (IL8) plasma membrane (Slc11a1)
Slc11a1 (Mus musculus)
IL8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 22 79.12 Quite High
cytokine 11 5.00 Very Low Very Low Very Low
interstitial cystitis 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
sodium channel 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Glutamate receptor 1 5.00 Very Low Very Low Very Low
Eae 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 26 90.00 High High
Bladder Cancer 9 82.16 Quite High
INFLAMMATION 26 79.12 Quite High
Recurrence 2 57.92 Quite High
Death 5 26.68 Quite Low
Overactive Bladder 18 5.00 Very Low Very Low Very Low
Mycobacterial Infection 4 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Interstitial Cystitis 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Others have presented evidence that BCG activates nuclear translocation of the transcription factor NF-kappaB, since pretreatment of with sulfasalazine, an inhibitor of NF-kappaB activity, blocked the ability of BCG to induce IL-8 secretion [48,49].
BCG Positive_regulation (induce) of Localization (secretion) of IL-8
1) Confidence 0.05 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2262873 Disease Relevance 0.58 Pain Relevance 0.08

General Comments

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