INT227016

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Context Info
Confidence 0.15
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.35
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TK1) small molecule metabolic process (TK1) kinase activity (TK1)
cytoplasm (TK1)
TK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 53.12 Quite High
anesthesia 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 112 95.44 Very High Very High Very High
Carcinoma 12 88.80 High High
Cancer 76 87.28 High High
Metastasis 4 80.28 Quite High
Inflammatory Breast Neoplasms 2 53.12 Quite High
Hypersensitivity 8 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 6 5.00 Very Low Very Low Very Low
Animal Mammary Neoplasms 2 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example the up-regulation of TK1 seen in WalBC cells has previously been associated with high proliferation activity and invasiveness potential which is related to a more aggressive phenotype [47].
Regulation (regulation) of TK1
1) Confidence 0.15 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2263075 Disease Relevance 0.94 Pain Relevance 0.03
Notably WalBC cells showed up regulated expression of DSP, s100A4, ANXA1, NDRG-1, TK1 and down regulation of genes such as tissue inhibitor of TIMP-3 and TAGLN.
Regulation (regulation) of TK1
2) Confidence 0.04 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2263075 Disease Relevance 0.41 Pain Relevance 0

General Comments

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