INT22716

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Context Info
Confidence 0.96
First Reported 1990
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 0.10
Pain Relevance 1.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (ENPEP) peptidase activity (ENPEP) cell-cell signaling (ENPEP)
ENPEP (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 31 100.00 Very High Very High Very High
Bioavailability 3 99.42 Very High Very High Very High
Neuropeptide 1 82.88 Quite High
antidepressant 3 52.16 Quite High
substance P 3 50.92 Quite High
sSRI 3 50.80 Quite High
antagonist 6 46.08 Quite Low
agonist 3 45.44 Quite Low
Triptan 3 45.20 Quite Low
Serotonin 3 44.72 Quite Low
Disease Link Frequency Relevance Heat
Disease 3 95.40 Very High Very High Very High
Cluster Headache 3 46.88 Quite Low
Intellectual Impairment 13 5.00 Very Low Very Low Very Low
Mental Disorders 8 5.00 Very Low Very Low Very Low
Emergencies 5 5.00 Very Low Very Low Very Low
Anxiety Disorder 4 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Confusion 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Aggression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We identified a number of clinically used drugs and biologically active endogenous peptides able to significantly decrease the rate of human plasmatic aminopeptidase (AP) leucine-enkephalin (LEU) degradation.
Protein_catabolism (degradation) of AP associated with enkephalin
1) Confidence 0.96 Published 2004 Journal Am J Ther Section Abstract Doc Link 15543085 Disease Relevance 0 Pain Relevance 0.42
We identified a number of clinically used drugs and biologically active endogenous peptides able to significantly decrease the rate of human plasmatic aminopeptidase (AP) leucine-enkephalin (LEU) degradation.
Protein_catabolism (degradation) of aminopeptidase associated with enkephalin
2) Confidence 0.84 Published 2004 Journal Am J Ther Section Abstract Doc Link 15543085 Disease Relevance 0 Pain Relevance 0.42
Aminopeptidase in human CSF which degrades delta-sleep inducing peptide (DSIP).
Protein_catabolism (degrades) of Aminopeptidase
3) Confidence 0.77 Published 1990 Journal Biochem. Biophys. Res. Commun. Section Title Doc Link 2322270 Disease Relevance 0 Pain Relevance 0.12
In this case, targeted modulation of the bioavailability of LEU and other endogenous AP-degraded hormonal and nonhormonal peptides could be useful in the treatment of the pathophysiology associated with various disease conditions.
Protein_catabolism (degraded) of AP associated with enkephalin, disease and bioavailability
4) Confidence 0.55 Published 2004 Journal Am J Ther Section Abstract Doc Link 15543085 Disease Relevance 0.10 Pain Relevance 0.53
The 2007 APA resolution against torture, to its credit, did include language that stated orders could not excuse torture or cruel, inhuman, and degrading treatment; although, whether this resolution truly supersedes Ethics Code provision 1.02 and whether actions like Dr.
Protein_catabolism (degrading) of APA
5) Confidence 0.48 Published 2008 Journal Philos Ethics Humanit Med Section Body Doc Link PMC2248202 Disease Relevance 0 Pain Relevance 0

General Comments

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