INT227255

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Context Info
Confidence 0.07
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.58
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
melanophores 1
fd (Mus musculus)
Pain Link Frequency Relevance Heat
nud 118 100.00 Very High Very High Very High
antidepressant 4 99.20 Very High Very High Very High
abdominal pain 6 73.72 Quite High
addiction 1 30.08 Quite Low
Central nervous system 4 5.00 Very Low Very Low Very Low
dexamethasone 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
melanocortin 1 receptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dyspepsia 118 100.00 Very High Very High Very High
Death 11 86.48 High High
Abdominal Pain 6 73.72 Quite High
Ulcers 16 65.64 Quite High
Disease 6 57.36 Quite High
Infection 14 44.56 Quite Low
Nicotine Addiction 4 43.32 Quite Low
Gastric Motility Disorder 6 37.84 Quite Low
Targeted Disruption 3 8.40 Low Low
Microphthalmia 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nevertheless, the role of gastric dysmotility in the progression of FD may be limited.
Gene_expression (progression) of FD associated with nud
1) Confidence 0.07 Published 2008 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2266051 Disease Relevance 0.65 Pain Relevance 0.32
There is no consensus on the issue of which drug is effective for FD [23–25].
Gene_expression (effective) of FD associated with nud
2) Confidence 0.07 Published 2008 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2266051 Disease Relevance 0.85 Pain Relevance 0.45
While a reduction of melanophores without a reduction in mitfa-expressing cells might have been consistent with a cell fate change of melanophores to xanthophores (because markers of melanoblasts and xanthoblasts are briefly co-expressed [32]), xanthophore numbers are equivalent in tfap2a deficient and tfap2a/e doubly-deficient embryos, arguing against such a fate transformation.
Gene_expression (deficient) of deficient in melanophores
3) Confidence 0.00 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2940735 Disease Relevance 0.09 Pain Relevance 0

General Comments

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