INT22739

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Context Info
Confidence 0.67
First Reported 1990
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 1.69
Pain Relevance 2.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (DYNLL1) transport (DYNLL1) mitochondrion (DYNLL1)
plasma membrane (DYNLL1) cytoskeleton (DYNLL1) nucleus (DYNLL1)
Anatomy Link Frequency
segmental bronchus 1
head 1
ulna 1
DYNLL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pin-prick hyperalgesia 2 100.00 Very High Very High Very High
imagery 1 99.68 Very High Very High Very High
Clonidine 7 99.32 Very High Very High Very High
lidocaine 5 99.20 Very High Very High Very High
Pain 9 96.76 Very High Very High Very High
Hyperalgesia 8 92.96 High High
Spinal cord 2 89.68 High High
Paresthesia 1 88.64 High High
sodium channel 1 86.56 High High
anesthesia 6 84.08 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 11 99.72 Very High Very High Very High
Pain 8 96.76 Very High Very High Very High
Dysesthesia 2 94.60 High High
Infection 1 93.24 High High
Pressure And Volume Under Development 1 88.96 High High
Sleep Disorders 1 87.96 High High
Aids-related Complex 2 85.60 High High
Contracture 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After induction of pin-prick hyperalgesia lidocaine or placebo was administered systemically using a double-blinded design.
Positive_regulation (induction) of pin associated with hyperalgesia, lidocaine and pin-prick hyperalgesia
1) Confidence 0.67 Published 2009 Journal J. Neurosci. Section Abstract Doc Link 19439594 Disease Relevance 0.79 Pain Relevance 1.35
The other four complications included drainage from a pin site, which resolved after removal of the pin: a three by two-centimeter skin slough, which spontaneously epithelialized; aseptic resorption of the distal end of the humerus and proximal end of the ulna, which stopped after immobilization and subsequent bracing of the elbow but resulted in moderate instability; and ulnar-nerve paresthesia, which was not operatively treated and persisted.
Positive_regulation (removal) of pin in ulna associated with paresthesia
2) Confidence 0.49 Published 1990 Journal J Bone Joint Surg Am Section Abstract Doc Link 2324148 Disease Relevance 0.63 Pain Relevance 0.10
Third, transient synchronization of afferents and efferents was most pronounced for pin-prick stimulation.
Positive_regulation (stimulation) of pin
3) Confidence 0.49 Published 1996 Journal Gen. Physiol. Biophys. Section Abstract Doc Link 8934198 Disease Relevance 0.09 Pain Relevance 0.17
We conclude that clonidine is effective in reducing the MAP increase with pin head-holder application in patients undergoing craniotomy.
Positive_regulation (increase) of pin in head associated with clonidine
4) Confidence 0.49 Published 1998 Journal Anesth. Analg. Section Abstract Doc Link 9585285 Disease Relevance 0.18 Pain Relevance 0.98
Accidental aspiration often results in the pin lodging in the segmental bronchus with the sharp end pointing cephalad.
Positive_regulation (results) of pin in segmental bronchus
5) Confidence 0.45 Published 1996 Journal J Trauma Section Abstract Doc Link 8614089 Disease Relevance 0 Pain Relevance 0.08

General Comments

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