INT227401

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Context Info
Confidence 0.51
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.26
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Nup210) nuclear envelope (Nup210) endoplasmic reticulum (Nup210)
nucleus (Nup210)
Anatomy Link Frequency
bile ducts 1
brain 1
Nup210 (Mus musculus)
Pain Link Frequency Relevance Heat
Bile 22 99.28 Very High Very High Very High
Hippocampus 1 95.68 Very High Very High Very High
Neurotransmitter 2 47.84 Quite Low
tolerance 2 40.72 Quite Low
member 8 2 35.12 Quite Low
pruritus 22 5.00 Very Low Very Low Very Low
fibrosis 6 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
Sicca syndrome 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Liver Failure 9 96.08 Very High Very High Very High
Biliary Liver Cirrhosis 150 89.40 High High
Apoptosis 8 86.92 High High
Syndrome 29 82.40 Quite High
Injury 8 80.40 Quite High
Hyperphagia 8 68.48 Quite High
Acute Liver Failure 1 66.36 Quite High
Anxiety Disorder 1 65.04 Quite High
Autoimmune Disease 11 59.36 Quite High
Disease 46 48.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A novel finding, not previously identified in other brain regions, is the reduced expression of four genes encoding nuclear porin structures, nucleoporins Nup107, Nup210, Nup43 and Nup205, which may reflect a change in nuclear transport during this period of development.


Gene_expression (expression) of Nup210 in brain
1) Confidence 0.51 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2827556 Disease Relevance 0.38 Pain Relevance 0.05
It has been shown that individuals who have sustained antibody response to gp210 antigen in the sera [82] or a high expression of gp210 antigen in small bile ducts in liver tissue [83], are at higher risk of progression to end-stage hepatic failure.
Gene_expression (expression) of gp210 in bile ducts associated with liver failure and bile
2) Confidence 0.15 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2266722 Disease Relevance 0.89 Pain Relevance 0.08

General Comments

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