INT227406

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.99
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Bcl2l10) mitochondrion (Bcl2l10) nucleus (Bcl2l10)
Anatomy Link Frequency
cardiomyocytes 1
Bcl2l10 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 2 99.52 Very High Very High Very High
cva 8 87.04 High High
Bile 22 70.40 Quite High
Inflammation 17 38.32 Quite Low
pruritus 22 5.00 Very Low Very Low Very Low
fibrosis 6 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
Sicca syndrome 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 137 100.00 Very High Very High Very High
Natriuresis 1 99.52 Very High Very High Very High
Biliary Liver Cirrhosis 150 95.44 Very High Very High Very High
Pressure And Volume Under Development 16 88.96 High High
Cv General 3 Under Development 5 87.04 High High
Death 36 85.16 High High
Injury 20 83.28 Quite High
Malaria 17 76.08 Quite High
Liver Failure 11 74.04 Quite High
Myocardial Infarction 5 73.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Down regulation of the anti-apoptotic protein, bcl-2 family, in injured portal tracts has been demonstrated to be a marker of ongoing apoptosis of cholangiocytes [85,86].
Regulation (regulation) of anti-apoptotic protein associated with apoptosis
1) Confidence 0.03 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2266722 Disease Relevance 1.14 Pain Relevance 0.08
Gene expression analysis of Pf-GPI-treated cardiomyocytes showed an up-regulation of both apoptotic genes (apaf-1, bax) and a myocardial damage marker (brain natriuretic peptide), while a down-regulation for the anti-apoptotic gene (bcl-2) was observed [24].


Regulation (regulation) of anti-apoptotic gene in cardiomyocytes associated with natriuresis and apoptosis
2) Confidence 0.00 Published 2010 Journal Parasit Vectors Section Body Doc Link PMC2995786 Disease Relevance 1.85 Pain Relevance 0.04

General Comments

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