INT22744

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Context Info
Confidence 0.10
First Reported 1990
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 0
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Penk) RNA binding (Gtf3a) nucleus (Gtf3a)
intracellular (Gtf3a) DNA binding (Gtf3a)
Anatomy Link Frequency
epididymis 5
spermatozoa 2
testis 1
Gtf3a (Rattus norvegicus)
Penk (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 8 99.50 Very High Very High Very High
Opioid 4 98.16 Very High Very High Very High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, the developmental profile of proenkephalin expression, coupled with the results of both surgical and pharmacological manipulations of the reproductive tract, indicate that spermatozoa, or a spermatozoa-associated factor, regulate proenkephalin gene expression in the epididymis.
factor Regulation (regulate) of Gene_expression (expression) of proenkephalin in spermatozoa
1) Confidence 0.10 Published 1990 Journal Mol. Endocrinol. Section Abstract Doc Link 2325661 Disease Relevance 0 Pain Relevance 0.05
A spermatozoa-associated factor regulates proenkephalin gene expression in the rat epididymis.
factor Regulation (regulates) of Gene_expression (expression) of proenkephalin in epididymis associated with enkephalin
2) Confidence 0.04 Published 1990 Journal Mol. Endocrinol. Section Title Doc Link 2325661 Disease Relevance 0 Pain Relevance 0.30
Castration studies demonstrate that a gonadal factor other than testosterone directly regulates epididymal proenkephalin expression, and the results of efferent duct ligation suggest that this factor must be supplied through an intact connection of the testis and epididymis.
factor Regulation (regulates) of Gene_expression (expression) of proenkephalin in epididymis
3) Confidence 0.04 Published 1990 Journal Mol. Endocrinol. Section Abstract Doc Link 2325661 Disease Relevance 0 Pain Relevance 0.07
Castration studies demonstrate that a gonadal factor other than testosterone directly regulates epididymal proenkephalin expression, and the results of efferent duct ligation suggest that this factor must be supplied through an intact connection of the testis and epididymis.
factor Regulation (regulates) of in testis Gene_expression (expression) of proenkephalin in epididymis
4) Confidence 0.01 Published 1990 Journal Mol. Endocrinol. Section Abstract Doc Link 2325661 Disease Relevance 0 Pain Relevance 0.07

General Comments

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