INT227457

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Context Info
Confidence 0.15
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 9
Total Number 10
Disease Relevance 3.19
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

CIMT (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 28 98.72 Very High Very High Very High
Biofeedback 45 94.40 High High
anesthesia 5 77.12 Quite High
rheumatoid arthritis 3 6.44 Low Low
agonist 50 5.00 Very Low Very Low Very Low
Inflammation 33 5.00 Very Low Very Low Very Low
Bile 16 5.00 Very Low Very Low Very Low
Angina 12 5.00 Very Low Very Low Very Low
aspirin 10 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 654 100.00 Very High Very High Very High
Metabolic Syndrome 30 99.10 Very High Very High Very High
Diabetes Mellitus 57 98.58 Very High Very High Very High
Atherosclerosis 166 94.28 High High
Hyperlipoproteinemia Type Ii 143 87.08 High High
Coronary Heart Disease 140 83.36 Quite High
Dyslipidemia /

Combined Dyslipidemia

24 79.44 Quite High
Hypertension 6 78.72 Quite High
Stroke 132 78.44 Quite High
Cardiovascular Disease 125 69.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In ENHANCE, patients were required to have LDL-C > 5.4 mmol/L (210 mg/dL) after washout of prior therapy, without minimal requirement for CIMT levels.
Neg (without) Positive_regulation (requirement) of Gene_expression (levels) of CIMT
1) Confidence 0.15 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988620 Disease Relevance 0.24 Pain Relevance 0
Baseline CIMT levels of ASAP and ENHANCE were ?
Positive_regulation (Baseline) of Gene_expression (levels) of CIMT
2) Confidence 0.15 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988620 Disease Relevance 0.24 Pain Relevance 0
Baseline levels of CIMT in SANDS trial were increased (mean, 0.9 mm).


Positive_regulation (increased) of Gene_expression (levels) of CIMT
3) Confidence 0.14 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988620 Disease Relevance 0.73 Pain Relevance 0.07
The advent of CIMT changed this perception and
Positive_regulation (advent) of Gene_expression (advent) of CIMT
4) Confidence 0.11 Published 2007 Journal Computational Intelligence and Neuroscience Section Body Doc Link PMC2266825 Disease Relevance 0.14 Pain Relevance 0.08
studies have shown that increases in bilateral cortical activation [16] are exhibited during CIMT;
Positive_regulation (increases) of Gene_expression (exhibited) of CIMT
5) Confidence 0.11 Published 2007 Journal Computational Intelligence and Neuroscience Section Body Doc Link PMC2266825 Disease Relevance 0 Pain Relevance 0.12
paper is that perhaps the CIMT process can be enhanced further for this group
Positive_regulation (enhanced) of Gene_expression (process) of CIMT
6) Confidence 0.11 Published 2007 Journal Computational Intelligence and Neuroscience Section Body Doc Link PMC2266825 Disease Relevance 0.05 Pain Relevance 0.09
that the benefits of CIMT could be extended to such patients through the
Positive_regulation (extended) of Gene_expression (benefits) of CIMT
7) Confidence 0.11 Published 2007 Journal Computational Intelligence and Neuroscience Section Body Doc Link PMC2266825 Disease Relevance 0.06 Pain Relevance 0.07
studies have shown that increases in bilateral cortical activation [16] are exhibited during CIMT;
Positive_regulation (during) of Gene_expression (exhibited) of CIMT
8) Confidence 0.11 Published 2007 Journal Computational Intelligence and Neuroscience Section Body Doc Link PMC2266825 Disease Relevance 0 Pain Relevance 0.12
0.027 mm and –0.041 mm, respectively; P < 0.001 versus statin monotherapy).51 High-risk patients with diabetes or the metabolic syndrome who were randomized to combination therapy, experienced somewhat greater regression of CIMT (?
Positive_regulation (experienced) of Gene_expression (regression) of CIMT associated with diabetes mellitus and metabolic syndrome
9) Confidence 0.03 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988622 Disease Relevance 0.81 Pain Relevance 0
More interestingly, a statistically significant inverse correlation between the increase in HDL and the regression of CIMT (P = 0.002) was noted suggesting that raising HDL with niacin ER over and above the statin treatment may account for the beneficial effect of atherosclerosis regression encountered.


Positive_regulation (increase) of Gene_expression (regression) of CIMT associated with atherosclerosis and disorder of lipid metabolism
10) Confidence 0.03 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988622 Disease Relevance 0.84 Pain Relevance 0

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