INT227485

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.91
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ptger2) plasma membrane (Ptger2) signal transducer activity (Ptger2)
pk (Mus musculus)
Ptger2 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 24 78.40 Quite High
Inflammation 12 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
nud 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ulcers 66 89.72 High High
Peptic Ulcer 12 76.92 Quite High
Wound Healing 2 73.48 Quite High
Injury 12 67.88 Quite High
Toxicity 4 30.88 Quite Low
Myelodysplastic Syndromes 28 5.00 Very Low Very Low Very Low
INFLAMMATION 16 5.00 Very Low Very Low Very Low
Stress 8 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 6 5.00 Very Low Very Low Very Low
Overdose 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PK augmented the mucosal PGE2 without showing any immediate effect.
PK Positive_regulation (augmented) of PGE2
1) Confidence 0.06 Published 2008 Journal BMC Complement Altern Med Section Body Doc Link PMC2266895 Disease Relevance 0.58 Pain Relevance 0.14
Thus, the upregulation of PGE2 by PK might contribute to its healing activity primarily via increasing the levels of mucin, and other growth factors, and to a lesser extent due to inhibition to gastric secretion.
PK Positive_regulation (upregulation) of PGE2
2) Confidence 0.05 Published 2008 Journal BMC Complement Altern Med Section Body Doc Link PMC2266895 Disease Relevance 0.33 Pain Relevance 0

General Comments

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