INT227511

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Context Info
Confidence 0.30
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.28
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (Hspa9) protein folding (Hspa9) mitochondrion (Hspa9)
enzyme binding (Hspa9) response to stress (Hspa9) cytoplasm (Hspa9)
Anatomy Link Frequency
muscle fibers 1
Hspa9 (Mus musculus)
Pain Link Frequency Relevance Heat
methotrexate 40 100.00 Very High Very High Very High
halothane 2 96.16 Very High Very High Very High
Inflammation 52 69.24 Quite High
Pain 13 5.00 Very Low Very Low Very Low
substance P 9 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
bradykinin 6 5.00 Very Low Very Low Very Low
Inflammatory stimuli 3 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myositis 42 77.52 Quite High
Stress 31 64.76 Quite High
Nociception 10 35.60 Quite Low
INFLAMMATION 48 5.00 Very Low Very Low Very Low
Pain 11 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Sprains And Strains 5 5.00 Very Low Very Low Very Low
Muscle Weakness 4 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, immunolabeling for Grp75 was not obligatorily related to the presence of sarcolemmal MHC-I immunoreactivity, in so far as it was detected also in those Group I and II patients who displayed MHC-I immunofluorescence only in a minor proportion of muscle fibers (grade +) (Figure 2k, l - arrows indicate MHC-I-positive fibers, arrowheads indicate negative fibers; compare with Figure 2i, j).
Grp75 Binding (immunolabeling) of in muscle fibers
1) Confidence 0.30 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888201 Disease Relevance 0.28 Pain Relevance 0.07
number among groups treated with MTX and/or CsA and/or vehicles.
CsA Binding (treated) of associated with methotrexate
2) Confidence 0.13 Published 2008 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2266974 Disease Relevance 0 Pain Relevance 0.12

General Comments

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