INT227542

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Context Info
Confidence 0.23
First Reported 2008
Last Reported 2008
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.20
Pain Relevance 1.92

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Prep) peptidase activity (Prep) mitochondrion (Mtx1)
nucleus (Prep) cytoplasm (Prep)
Mtx1 (Mus musculus)
Prep (Mus musculus)
Pain Link Frequency Relevance Heat
methotrexate 80 100.00 Very High Very High Very High
substance P 18 98.32 Very High Very High Very High
bradykinin 12 97.56 Very High Very High Very High
Pain 26 91.36 High High
tolerance 4 90.96 High High
Spinal cord 2 78.24 Quite High
Glutamate 2 77.64 Quite High
central sensitization 2 76.44 Quite High
Inflammation 34 73.68 Quite High
Hyperalgesia 6 73.68 Quite High
Disease Link Frequency Relevance Heat
Pain 22 91.36 High High
INFLAMMATION 38 73.68 Quite High
Hyperalgesia 6 73.68 Quite High
Arthritis 4 64.88 Quite High
Seronegative Spondarthritis 2 30.88 Quite Low
Organ Transplantation 2 23.24 Low Low
Headache 2 20.80 Low Low
Nociception 20 12.56 Low Low
Sleep Disorders 2 7.88 Low Low
Depression 2 7.24 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since MTX or MTX plus CsA increased POP activity but did not
MTX Neg (not) Positive_regulation (increased) of POP Binding (activity) of associated with methotrexate
1) Confidence 0.23 Published 2008 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2266974 Disease Relevance 0.60 Pain Relevance 0.96
Since MTX or MTX plus CsA increased POP activity but did not
MTX Neg (not) Positive_regulation (increased) of POP Binding (activity) of associated with methotrexate
2) Confidence 0.23 Published 2008 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2266974 Disease Relevance 0.60 Pain Relevance 0.96

General Comments

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