INT227557

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.66
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
fat 1
thyroid 1
T lymphocytes 1
FAM155B (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 3 97.24 Very High Very High Very High
cytokine 18 96.16 Very High Very High Very High
Inflammation 102 91.92 High High
fibrosis 9 89.12 High High
tolerance 6 74.64 Quite High
corticosteroid 3 37.68 Quite Low
agonist 27 5.00 Very Low Very Low Very Low
antagonist 12 5.00 Very Low Very Low Very Low
chemokine 9 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Eye Disease 189 100.00 Very High Very High Very High
Graves' Ophthalmopathy 6 99.76 Very High Very High Very High
Disease 78 99.44 Very High Very High Very High
Diplopia 3 98.56 Very High Very High Very High
Autoimmune Disease 12 98.52 Very High Very High Very High
Optic Disorders 3 97.96 Very High Very High Very High
Pain 3 97.24 Very High Very High Very High
Disorders Of The Lacrimal System 3 97.00 Very High Very High Very High
Pressure And Volume Under Development 6 95.88 Very High Very High Very High
Ocular Toxicity (including Many Sub-types) 9 92.40 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TED is closely associated with Graves' disease (GD), a common autoimmune disorder in which stimulatory autoantibodies against the thyroid-stimulating hormone receptor (TSH-R) cause the thyroid to produce excess thyroid hormone [50, 54, 58, 59].
TED Binding (associated) of in thyroid associated with autoimmune disease, graves' ophthalmopathy, disease and eye disease
1) Confidence 0.08 Published 2008 Journal PPAR Research Section Body Doc Link PMC2266979 Disease Relevance 2.24 Pain Relevance 0.22
Autoimmune responses, like that found with TED, are governed primarily by the actions of B and T lymphocytes.
TED Binding (found) of in T lymphocytes associated with eye disease
2) Confidence 0.06 Published 2008 Journal PPAR Research Section Body Doc Link PMC2266979 Disease Relevance 0.52 Pain Relevance 0.12
activation is also critical to adipogenesis, making it a potential culprit in the pathological fat accumulation associated with TED.
TED Binding (associated) of in fat associated with eye disease
3) Confidence 0.06 Published 2008 Journal PPAR Research Section Abstract Doc Link PMC2266979 Disease Relevance 0.90 Pain Relevance 0.12

General Comments

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