INT227566

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 2
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NR3C1) aging (NR3C1) intracellular (NR3C1)
protein complex (NR3C1) cytoplasm (NR3C1) cytosol (NR3C1)
NR3C1 (Homo sapiens)
RS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 48 100.00 Very High Very High Very High
Serotonin 16 100.00 Very High Very High Very High
Dopamine 12 5.00 Very Low Very Low Very Low
antagonist 12 5.00 Very Low Very Low Very Low
Potency 8 5.00 Very Low Very Low Very Low
Opioid 4 5.00 Very Low Very Low Very Low
opioid receptor 4 5.00 Very Low Very Low Very Low
Enkephalin 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 8 5.00 Very Low Very Low Very Low
Osteoporosis 2 5.00 Very Low Very Low Very Low
Bordatella Infection 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Coronary Heart Disease 2 5.00 Very Low Very Low Very Low
Influenza Virus Infection 2 5.00 Very Low Very Low Very Low
Hydrocephalus 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The first receptor in this series, 5-HT4-D100A or Rs1 (RASSL serotonin 1), is not activated by its endogenous agonist, serotonin, but is selectively activated by the small synthetic molecules GR113808, GR125487, and RO110-0235.
GR113808 Neg (not) Positive_regulation (activated) of Rs1 associated with agonist and serotonin
1) Confidence 0.01 Published 2007 Journal PLoS ONE Section Abstract Doc Link PMC2267039 Disease Relevance 0 Pain Relevance 0.20
The first receptor in this series, 5-HT4-D100A or Rs1 (RASSL serotonin 1), is not activated by its endogenous agonist, serotonin, but is selectively activated by the small synthetic molecules GR113808, GR125487, and RO110-0235.
GR125487 Neg (not) Positive_regulation (activated) of Rs1 associated with agonist and serotonin
2) Confidence 0.01 Published 2007 Journal PLoS ONE Section Abstract Doc Link PMC2267039 Disease Relevance 0 Pain Relevance 0.20

General Comments

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