INT227667

Context Info Confidence 0.27 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 0.24 Pain Relevance 0

extracellular space (MSTN) growth (MSTN) extracellular region (MSTN) cytoplasm (MSTN)

Anatomy Link Frequency muscle 2 MSTN (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 4 5.00 lidocaine 2 5.00 cytokine 2 5.00 anesthesia 2 5.00 imagery 2 5.00 alcohol 2 5.00

Disease Link Frequency Relevance Heat Aging 18 66.60 Injury 4 55.36 Rheumatoid Arthritis 16 5.00 INFLAMMATION 4 5.00 Hypertension 2 5.00 Hypoxia 2 5.00 Testosterone Deficiency 2 5.00 Body Weight 2 5.00 Frailty 2 5.00 Muscular Atrophy 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Furthermore, the expression in muscle of mRNA for myostatin and myoD, cell regulatory proteins affecting muscle size [26]–[29], was not different between the sexes, which makes it unlikely that they are involved in regulating the basal rate of MPS, although, we cannot from our data rule out differences in the muscle myostatin and myoD protein concentration (and thus in cell function).

Transcription (expression) of myostatin in muscle

1) Confidence 0.27 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2267222 Disease Relevance 0.17 Pain Relevance 0

The postabsorptive muscle mRNA concentrations for myoD and myostatin were not different between sexes; feeding doubled myoD mRNA (P<0.05) and halved that of myostatin (P<0.05) in both sexes.

Transcription (concentrations) of myostatin in muscle

2) Confidence 0.21 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2267222 Disease Relevance 0.07 Pain Relevance 0

General Comments

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