INT22770

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.44
First Reported 1990
Last Reported 2010
Negated 4
Speculated 0
Reported most in Body
Documents 5
Total Number 7
Disease Relevance 2.56
Pain Relevance 1.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Egf) plasma membrane (Egf)
Anatomy Link Frequency
superior 2
Gastric juice 2
Egf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
peptic ulcer disease 3 99.28 Very High Very High Very High
Arthritis 56 98.02 Very High Very High Very High
rheumatoid arthritis 15 96.12 Very High Very High Very High
spinal inflammation 6 86.88 High High
cytokine 57 74.76 Quite High
psoriasis 11 72.32 Quite High
Inflammation 3 51.60 Quite High
ischemia 21 29.44 Quite Low
Glutamate 12 13.84 Low Low
antagonist 15 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ulcers 9 99.28 Very High Very High Very High
Disease 13 98.76 Very High Very High Very High
Arthritis 9 98.02 Very High Very High Very High
Rheumatoid Arthritis 16 96.12 Very High Very High Very High
Injury 105 91.96 High High
Duodenal Ulcer 2 90.12 High High
Peptic Ulcer 5 88.68 High High
Low Back Pain 13 86.88 High High
Seronegative Spondarthritis 48 73.36 Quite High
Psoriasis 11 72.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: Salivary EGF levels were not different between both groups of subjects (4.2 +/- 0.34 vs. 5 +/- 0.54 ng/mg protein, NS), and HPLC revealed that salivary EGF in both groups had similar molecular weights.
Neg (not) Regulation (different) of Gene_expression (levels) of EGF
1) Confidence 0.44 Published 2001 Journal Nephron Section Body Doc Link 11244307 Disease Relevance 0.18 Pain Relevance 0
CONCLUSION: Nocloprost is superior to ranitidine in the treatment of chronic gastric ulcers, and these effects could be due, at least in part, to higher expression and mucosal content of EGF in the ulcer area.


Regulation (due) of Gene_expression (expression) of EGF in superior
2) Confidence 0.36 Published 1997 Journal Scand. J. Gastroenterol. Section Body Doc Link 9361169 Disease Relevance 0 Pain Relevance 0
Gastric juice immunoreactive epidermal growth factor levels in patients with peptic ulcer disease.
Regulation (immunoreactive) of Gene_expression (levels) of epidermal growth factor in Gastric juice associated with peptic ulcer disease and disease
3) Confidence 0.31 Published 1990 Journal Am. J. Gastroenterol. Section Title Doc Link 2327382 Disease Relevance 0.60 Pain Relevance 0.16
As reported here, as well as in a recently published study, we found that there was no change in the expression of EGF in the SVZ after neonatal H/I.
Neg (no) Regulation (change) of Gene_expression (expression) of EGF
4) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2832687 Disease Relevance 0.12 Pain Relevance 0.06
Both FGF1 and FGF2 have been observed to be upregulated in the synovial tissue of human subjects with RA [25] and significantly worsened clinical symptoms in a rat adjuvant-induced model of arthritis [26], while at least one polymorphism of the EGF gene (rs4444903) has been shown to significantly affect EGF production [27].
Regulation (affect) of Gene_expression (production) of EGF associated with rheumatoid arthritis and arthritis
5) Confidence 0.22 Published 2007 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1781940 Disease Relevance 1.50 Pain Relevance 0.82
QPCR revealed no change in EGF mRNA expression at 7 days of recovery from H/I between ILH and CLH [23].
Neg (no) Regulation (change) of Gene_expression (expression) of EGF mRNA
6) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2832687 Disease Relevance 0.16 Pain Relevance 0
-treated cells was unaffected by the presence of either EGF, LIF or a combination of both LIF and TGF?
Neg (unaffected) Regulation (unaffected) of Gene_expression (presence) of EGF
7) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2832687 Disease Relevance 0 Pain Relevance 0.07

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox