INT227717

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.66
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
embryo 1
precursor cells 1
S12 (Homo sapiens)
Pain Link Frequency Relevance Heat
GABA receptor 6 95.32 Very High Very High Very High
gABA 15 84.48 Quite High
Neuritis 3 71.92 Quite High
Glutamate 3 55.92 Quite High
tolerance 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 12 99.08 Very High Very High Very High
Apoptosis 3 95.84 Very High Very High Very High
Hypertension 3 91.80 High High
Death 9 86.00 High High
Glaucoma 3 81.76 Quite High
Neuritis 3 71.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that the expression of seven of the thirteen proteins (54%), S1 through S5, S12, and S13, was increased in ED11 of embryo chick retina and six (46%), S6 through S11, were decreased (Table 1).
Gene_expression (expression) of S12 in embryo
1) Confidence 0.05 Published 2008 Journal Proteome Sci Section Body Doc Link PMC2267454 Disease Relevance 0 Pain Relevance 0.03
Flice (S12), also called caspase-8, was expressed in axotomized retinal ganglion cells (RGCs) [35] and flice is activated in 7-keratocholesterol-induced apoptosis in R28, retinal precursor cells [36].
Gene_expression (expressed) of S12 in precursor cells associated with ganglion cysts and apoptosis
2) Confidence 0.04 Published 2008 Journal Proteome Sci Section Body Doc Link PMC2267454 Disease Relevance 0.52 Pain Relevance 0.24
In ED15, an expression of flice (S12) in ED15 was undetectable by PD-Quest software analysis.


Gene_expression (expression) of S12
3) Confidence 0.03 Published 2008 Journal Proteome Sci Section Body Doc Link PMC2267454 Disease Relevance 0.14 Pain Relevance 0.11

General Comments

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