INT227795

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.21
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 3.05
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Acsl1) endoplasmic reticulum (Acsl1) plasma membrane (Acsl1)
peroxisome (Acsl1) ligase activity (Acsl1) lipid metabolic process (Acsl1)
Anatomy Link Frequency
urine 2
nucleus 1
Acsl1 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 3 83.52 Quite High
cINOD 10 68.80 Quite High
diclofenac 1 68.24 Quite High
tolerance 1 44.60 Quite Low
agonist 1 34.32 Quite Low
Inflammation 7 5.00 Very Low Very Low Very Low
cva 7 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acute Coronary Syndrome 44 100.00 Very High Very High Very High
Sprains And Strains 282 99.16 Very High Very High Very High
Coronary Artery Disease 56 99.04 Very High Very High Very High
Urinary Tract Infection 234 97.24 Very High Very High Very High
Infection 127 92.12 High High
Cystitis 60 76.88 Quite High
Hypertrophy 3 73.96 Quite High
Coronary Heart Disease 1 72.20 Quite High
Myocardial Infarction 12 68.08 Quite High
Dyslipidemia /

Combined Dyslipidemia

2 65.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In detail, when the ACS, CHD and control groups were compared with respect to eNOS T-786C genotypes, the CC genotype frequency was found to be the most prevalent in ACS group in comparison to CHD and control groups (p = 0.001).
Negative_regulation (prevalent) of ACS associated with acute coronary syndrome and coronary artery disease
1) Confidence 0.21 Published 2008 Journal Lipids Health Dis Section Body Doc Link PMC2267783 Disease Relevance 1.74 Pain Relevance 0
This is further supported by ibuprofen suppression of other PPAR-related genes, such as ACS and FABP3 (Figure 3); the latter of these two genes encodes fatty acid binding protein 3, which is involved in transporting PPAR ligands to the nucleus [35].
Negative_regulation (suppression) of ACS in nucleus
2) Confidence 0.12 Published 2008 Journal Genome Biol Section Body Doc Link PMC2374704 Disease Relevance 0 Pain Relevance 0.10
The gene encoding acetyl-CoA synthetase, acs, was one of the most strongly downregulated genes in all E. coli strains during growth in urine from women with UTI as compared to culture in urine ex vivo (Table 3).
Negative_regulation (downregulated) of acetyl-CoA synthetase in urine associated with sprains and strains and urinary tract infection
3) Confidence 0.09 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2978726 Disease Relevance 0.45 Pain Relevance 0.04
By qPCR, acs was downregulated nearly 600-fold in vivo, while ackA was relatively unchanged (Fig. 1B).
Negative_regulation (downregulated) of acs
4) Confidence 0.09 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2978726 Disease Relevance 0.36 Pain Relevance 0.03
The gene encoding acetyl-CoA synthetase, acs, was one of the most strongly downregulated genes in all E. coli strains during growth in urine from women with UTI as compared to culture in urine ex vivo (Table 3).
Negative_regulation (downregulated) of acs in urine associated with sprains and strains and urinary tract infection
5) Confidence 0.09 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2978726 Disease Relevance 0.44 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox