INT227830

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Context Info
Confidence 0.11
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (ERCC6) signal transduction (CSH1) extracellular region (CSH1)
nucleolus (ERCC6) nucleus (ERCC6) DNA binding (ERCC6)
CSH1 (Homo sapiens)
ERCC6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Glutamate receptor 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Freckles 2 43.60 Quite Low
Syndrome 3 40.88 Quite Low
Cockayne Syndrome 55 37.80 Quite Low
Disease 4 30.68 Quite Low
Contagious Ecthyma 6 5.00 Very Low Very Low Very Low
Hutchinson-gilford Progeria Syndrome 4 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Osteogenic Sarcomas 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This could also explain why CSA mutations are clinically indistinguishable from CSB mutations: Failure of CSA to target CSB [68] for ubiquitin-dependent degradation after CSB-dependent repair could have the same effect as the fusion protein in the absence of CSB — freezing repair complexes in place, and blocking subsequent events.
CSA Regulation (target) of CSB
1) Confidence 0.11 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2268245 Disease Relevance 0 Pain Relevance 0

General Comments

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