INT227910

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Context Info
Confidence 0.22
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (TNF, IL10) extracellular space (TNF, IL10) extracellular region (TNF, IL10)
extracellular matrix organization (TNF) cell-cell signaling (IL10) response to stress (IL10)
TNF (Homo sapiens)
IL10 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 1 99.84 Very High Very High Very High
metalloproteinase 9 86.40 High High
Osteoarthritis 37 78.72 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
Tendonitis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 1 99.84 Very High Very High Very High
Synovitis 1 99.00 Very High Very High Very High
Osteoarthritis 12 89.36 High High
Knee Osteoarthritis 36 78.72 Quite High
Shock 5 50.00 Quite Low
Necrosis 2 50.00 Quite Low
Cancer 1 50.00 Quite Low
Frailty 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additionally, it remains to be clarified whether IL-10 decrease is a specific outcome of ESW treatment or mediated by TNF-alpha reduction since it has been shown that TNF-alpha up-regulates IL-10 expression in rheumatoid arthritis synovitis [20].
TNF-alpha Positive_regulation (regulates) of Gene_expression (expression) of IL-10 associated with synovitis and rheumatoid arthritis
1) Confidence 0.22 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2268688 Disease Relevance 0.68 Pain Relevance 0.29

General Comments

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