INT228038

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Context Info
Confidence 0.07
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.02
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (Tbce) protein folding (Tbce) cytoskeleton (Tbce)
cytoplasm (Tbce)
Tbce (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 58 100.00 Very High Very High Very High
lidocaine 102 96.00 Very High Very High Very High
Spinal cord 57 89.84 High High
Inflammation 137 80.68 Quite High
Central nervous system 29 58.72 Quite High
local anesthetic 6 37.12 Quite Low
Inflammatory stimuli 2 35.76 Quite Low
isoflurane 42 26.24 Quite Low
Inflammatory response 17 5.00 Very Low Very Low Very Low
chemokine 15 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endotoxemia 1 99.66 Very High Very High Very High
Lung Injury 7 94.96 High High
Adult Respiratory Distress Syndrome 14 92.20 High High
Spinal Cord Injury 70 86.56 High High
Injury 75 81.64 Quite High
INFLAMMATION 143 80.68 Quite High
Peritonitis 6 69.28 Quite High
Pneumonia 14 68.08 Quite High
Shock 1 67.80 Quite High
Atypical Pneumonia 2 66.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In rabbits, mechanical ventilation during endotoxemia synergistically increases alveolar polymorphonuclear cell (PMN) recruitment and cytokine expression in BALF beyond that seen with either endotoxin or mechanical ventilation alone [7,8].
Positive_regulation (increases) of Gene_expression (expression) of PMN associated with endotoxemia and cytokine
1) Confidence 0.07 Published 2010 Journal BMC Pulm Med Section Body Doc Link PMC3002319 Disease Relevance 1.24 Pain Relevance 0.16
The increase in exudate PMN was ?
Positive_regulation (increase) of Gene_expression (exudate) of PMN
2) Confidence 0.05 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2268966 Disease Relevance 0.34 Pain Relevance 0.66
Our data confirm C3 expression by PMNs in culture, and demonstrate the expression of C1q and C4 by PMNs, providing a more complete characterization of PMN expression of the early complement proteins in culture.
Positive_regulation (providing) of Gene_expression (expression) of PMN
3) Confidence 0.00 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2443364 Disease Relevance 0.44 Pain Relevance 0.19

General Comments

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