INT22804

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Context Info
Confidence 0.41
First Reported 1981
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 8
Total Number 8
Disease Relevance 8.07
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ALDOC) small molecule metabolic process (ALDOC) lyase activity (ALDOC)
aging (ALDOC) carbohydrate metabolic process (ALDOC) cytoplasm (ALDOC)
Anatomy Link Frequency
muscle 2
skin 1
ALDOC (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 10 95.56 Very High Very High Very High
corticosteroid 3 93.40 High High
Inflammation 8 93.32 High High
lumbar region 1 57.76 Quite High
Arthritis 2 53.92 Quite High
withdrawal 1 53.76 Quite High
beta blocker 1 43.44 Quite Low
imagery 6 27.12 Quite Low
alcohol 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dermatomyositis 21 99.50 Very High Very High Very High
Rhinitis 9 98.80 Very High Very High Very High
Eosinophilia 3 98.64 Very High Very High Very High
Disease 6 98.48 Very High Very High Very High
Muscle Weakness 12 97.76 Very High Very High Very High
Synovitis 9 97.60 Very High Very High Very High
Frailty 11 96.40 Very High Very High Very High
Myalgia 7 95.92 Very High Very High Very High
Arthralgia 9 95.56 Very High Very High Very High
Pressure And Volume Under Development 5 94.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
He had never complained of muscle symptoms, and his laboratory examinations showed no elevation of either CPK or aldolase.
Neg (no) Positive_regulation (elevation) of aldolase in muscle
1) Confidence 0.41 Published 2002 Journal Nihon Kokyuki Gakkai Zasshi Section Abstract Doc Link 12325332 Disease Relevance 0.87 Pain Relevance 0.09
Eosinophilia was not found and serum creatine kinase activity was normal, while aldolase was markedly elevated.
Positive_regulation (elevated) of aldolase associated with eosinophilia
2) Confidence 0.41 Published 2009 Journal Rinsho Shinkeigaku Section Abstract Doc Link 19348178 Disease Relevance 1.29 Pain Relevance 0.22
The serum aldolase activity is usuful for diagnosis and for monitoring the disease activity.
Positive_regulation (usuful) of aldolase associated with disease
3) Confidence 0.39 Published 2009 Journal Rinsho Shinkeigaku Section Abstract Doc Link 19348178 Disease Relevance 1.25 Pain Relevance 0.19
[Elevated serum aldolase activity in a patient of non-eosinophilic myofasciitis and synovitis with perifascicular atrophy].
Positive_regulation (Elevated) of aldolase associated with rhinitis, frailty and synovitis
4) Confidence 0.36 Published 2009 Journal Rinsho Shinkeigaku Section Title Doc Link 19348178 Disease Relevance 1.29 Pain Relevance 0.22
He was diagnosed as dermatomyositis by acceleration of ESR, elevation of GOT, GPT, CPK, aldolase, moderate increases of collagen fibers in biopsy specimen of skin and his clinical signs.
Positive_regulation (elevation) of aldolase in skin associated with dermatomyositis
5) Confidence 0.17 Published 1981 Journal Hokkaido Igaku Zasshi Section Abstract Doc Link 7262822 Disease Relevance 0.95 Pain Relevance 0.09
Laboratory data showed significant increase of serum CK, aldolase and myoglobin.
Positive_regulation (increase) of aldolase
6) Confidence 0.15 Published 1990 Journal Rinsho Shinkeigaku Section Abstract Doc Link 2331815 Disease Relevance 0.54 Pain Relevance 0.03
Elevations in serum CK, LDH, aldolase, and aminotransferases occur in most patients.
Positive_regulation (Elevations) of aldolase
7) Confidence 0.09 Published 2008 Journal Cases J Section Body Doc Link PMC2584084 Disease Relevance 1.28 Pain Relevance 0.11
Routine laboratory findings only showed mildly elevated levels of muscle-origin enzymes including CK and aldolase.
Positive_regulation (elevated) of aldolase in muscle
8) Confidence 0.06 Published 2003 Journal Rinsho Shinkeigaku Section Abstract Doc Link 12931630 Disease Relevance 0.60 Pain Relevance 0.08

General Comments

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