INT228050

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.96
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (Tbce) protein folding (Tbce) cytoskeleton (Tbce)
cytoplasm (Tbce)
Anatomy Link Frequency
macrophage 2
Tbce (Mus musculus)
Pain Link Frequency Relevance Heat
lidocaine 102 98.06 Very High Very High Very High
Inflammation 102 97.28 Very High Very High Very High
isoflurane 35 86.32 High High
local anesthetic 6 83.88 Quite High
cytokine 28 25.00 Low Low
chemokine 15 25.00 Low Low
Inflammatory response 9 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 20 99.34 Very High Very High Very High
INFLAMMATION 111 97.28 Very High Very High Very High
Peritonitis 6 90.52 High High
Cramps 11 46.40 Quite Low
Injury 7 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Htlv Types I And Ii 3 5.00 Very Low Very Low Very Low
Burns 2 5.00 Very Low Very Low Very Low
Overdose 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Lidocaine inhibited both PMN apoptosis and macrophage uptake of apoptotic PMN, events that contributed to impaired PMN removal from exudates and thereby delayed the onset of resolution of acute inflammation and return to homeostasis.
Negative_regulation (impaired) of Negative_regulation (removal) of PMN in macrophage associated with inflammation, apoptosis and lidocaine
1) Confidence 0.04 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2268966 Disease Relevance 0.96 Pain Relevance 1.02

General Comments

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