INT228087

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Context Info
Confidence 0.29
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.08
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Chrm2) plasma membrane (Chrm2) signal transducer activity (Chrm2)
Anatomy Link Frequency
splenic macrophages 1
dendritic cells 1
Chrm2 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 35 76.80 Quite High
Inflammation 66 74.72 Quite High
Inflammatory stimuli 4 49.76 Quite Low
agonist 8 38.64 Quite Low
Kinase C 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lymphatic System Cancer 5 98.20 Very High Very High Very High
Cancer 81 97.04 Very High Very High Very High
Aggression 1 82.52 Quite High
Splenomegaly 1 81.60 Quite High
INFLAMMATION 76 74.72 Quite High
Malignant Neoplastic Disease 1 55.96 Quite High
Lung Cancer 1 51.64 Quite High
Infection 49 46.24 Quite Low
Metabolic Disorder 1 34.16 Quite Low
Confusion 1 16.32 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, these investigators showed that M2 is transcribed by infected dendritic cells, although they did not demonstrate that IL-10 secretion was mediated by M2 [36].
Transcription (transcribed) of M2 in dendritic cells
1) Confidence 0.29 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2270344 Disease Relevance 0.08 Pain Relevance 0.03
mRNA expression in M2-oriented TAM and splenic macrophages
Transcription (expression) of M2 in splenic macrophages
2) Confidence 0.08 Published 2008 Journal PPAR Research Section Body Doc Link PMC2443396 Disease Relevance 1.00 Pain Relevance 0.10

General Comments

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