INT228096

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Context Info
Confidence 0.39
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.43
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
spleens 2
T cells 2
Cd8a (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 33 96.56 Very High Very High Very High
tolerance 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Immunization 7 99.60 Very High Very High Very High
Infection 45 74.64 Quite High
Epstein-barr Virus 24 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 10 5.00 Very Low Very Low Very Low
Hypersensitivity 5 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 4 5.00 Very Low Very Low Very Low
Sarcoma 3 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Contagious Ecthyma 3 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results showed that a significantly higher expression of CD94-NKG2A heterodimer on CD8+T cells was induced following OVA inoculation into the anterior chamber, and that AC-injection of antigen and immunization have a synergistic effect on the increase of CD8+CD94+T cells.
Regulation (effect) of Positive_regulation (increase) of CD8 in T cells associated with immunization
1) Confidence 0.39 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2566975 Disease Relevance 0.17 Pain Relevance 0.09
In contrast, there was no global change in overall CD8 activation as determined by the percentage of CD8+ CD11ahigh T cells in the spleens of infected mice (Figure 7D).
Neg (no) Regulation (change) of Positive_regulation (activation) of CD8 in spleens
2) Confidence 0.04 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2270344 Disease Relevance 0.26 Pain Relevance 0

General Comments

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