INT228117

Context Info Confidence 0.22 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.61 Pain Relevance 0

extracellular space (Il10) signal transduction (Chrm2) extracellular region (Il10) intracellular (Il10) plasma membrane (Chrm2) signal transducer activity (Chrm2)

Chrm2 (Mus musculus) Il10 (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 22 5.00 chemokine 1 5.00 anesthesia 1 5.00 Potency 1 5.00

Disease Link Frequency Relevance Heat Infection 45 98.68 Epstein-barr Virus 24 87.36 Sarcoma 3 25.00 Cytomegalovirus Infection 10 5.00 Lymphatic System Cancer 4 5.00 Apoptosis 3 5.00 Contagious Ecthyma 3 5.00 Sprains And Strains 2 5.00 Salivary Gland Disease 2 5.00 Sleep Disorders 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Here we show that a unique MHV68 latency-associated gene product, the M2 protein, is required for the elevated serum IL-10 levels observed at 2 weeks post-infection.

M2 Positive_regulation (required) of Positive_regulation (elevated) of IL-10 associated with infection

1) Confidence 0.22 Published 2008 Journal PLoS Pathogens Section Abstract Doc Link PMC2270344 Disease Relevance 0.61 Pain Relevance 0

General Comments

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