INT228118

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Context Info
Confidence 0.11
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.21
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Fyn) mitochondrion (Fyn) intracellular (Vav1)
plasma membrane (Fyn) kinase activity (Fyn)
Anatomy Link Frequency
B cells 1
Fyn (Mus musculus)
Vav1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 22 33.16 Quite Low
chemokine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 3 87.60 High High
Infection 45 61.56 Quite High
Sprains And Strains 2 49.40 Quite Low
Epstein-barr Virus 24 12.12 Low Low
Cytomegalovirus Infection 10 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 4 5.00 Very Low Very Low Very Low
Sarcoma 3 5.00 Very Low Very Low Very Low
Contagious Ecthyma 3 5.00 Very Low Very Low Very Low
Salivary Gland Disease 2 5.00 Very Low Very Low Very Low
Sleep Disorders 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
M2 co-immunoprecipitates with Vav1 in S11 B cells, a MHV68 latently infected cell line, and M2 and Vav1 overexpression in A20 B cells leads to Vav1 phosphorylation, trimerization with Fyn, and downstream activation of Rac1 [27].
Fyn Binding (trimerization) of Vav1 in B cells
1) Confidence 0.11 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2270344 Disease Relevance 0.21 Pain Relevance 0

General Comments

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