INT228136

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Context Info
Confidence 0.14
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Fasl) extracellular space (Fasl) extracellular region (Fasl)
cytoplasmic membrane-bounded vesicle (Fasl) plasma membrane (Fasl) lysosome (Fasl)
Anatomy Link Frequency
T cells 2
Trav6-3 (Mus musculus)
Fasl (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 12 82.96 Quite High
withdrawal 3 18.16 Low Low
anesthesia 2 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 24 98.04 Very High Very High Very High
Splenomegaly 5 94.84 High High
Lymphadenopathy 13 94.16 High High
Apoptosis 37 63.76 Quite High
Death 32 60.80 Quite High
Cold Sores 18 33.00 Quite Low
Herpes Simplex Virus 18 5.00 Very Low Very Low Very Low
Autoimmune Disease 7 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It appears likely that repeated TCR stimulation causes activation of the FasL-Fas signaling pathway in T cells during chronic infection (Brunner et al., 1995; Dhein et al., 1995), but how Bim is induced in this setting is less clear.
TCR Positive_regulation (causes) of Positive_regulation (activation) of FasL in T cells associated with infection
1) Confidence 0.14 Published 2008 Journal Immunity Section Body Doc Link PMC2270348 Disease Relevance 0.59 Pain Relevance 0.04

General Comments

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