INT228162

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Context Info
Confidence 0.38
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.29
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Adipoq) extracellular region (Adipoq) endoplasmic reticulum (Adipoq)
Adipoq (Mus musculus)
Pain Link Frequency Relevance Heat
dexamethasone 2 99.88 Very High Very High Very High
tolerance 26 81.56 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 64 94.92 High High
Targeted Disruption 20 82.92 Quite High
Impaired Glucose Tolerance 18 80.44 Quite High
Hyperinsulinism 6 79.52 Quite High
Diabetes Mellitus 42 54.24 Quite High
Insulin Resistance 6 26.80 Quite Low
Metabolic Syndrome 10 5.00 Very Low Very Low Very Low
Body Weight 10 5.00 Very Low Very Low Very Low
Atherosclerosis 8 5.00 Very Low Very Low Very Low
Dyslipidemia /

Combined Dyslipidemia

4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the 11th day from the start of differentiation (before the peak of adiponectin secretion), dexamethasone was removed from the medium. 24 hours later, the cells were subjected to treatments as follows: medium only, 100 nM cortisone, 0.1 ?
Negative_regulation (peak) of Localization (secretion) of adiponectin associated with dexamethasone
1) Confidence 0.38 Published 2008 Journal BMC Pharmacol Section Body Doc Link PMC2270815 Disease Relevance 0.29 Pain Relevance 0.05
This is in accordance with other studies where glucocorticoid is reported to inhibit both expression and secretion of adiponectin [6,28].
Negative_regulation (inhibit) of Localization (secretion) of adiponectin
2) Confidence 0.34 Published 2008 Journal BMC Pharmacol Section Body Doc Link PMC2270815 Disease Relevance 1.01 Pain Relevance 0.12

General Comments

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