INT228168

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.08
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Adipoq) extracellular region (Adipoq) endoplasmic reticulum (Adipoq)
nucleus (Prkag1) protein complex (Prkag1) response to stress (Prkag1)
Adipoq (Mus musculus)
Prkag1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 18 100.00 Very High Very High Very High
tolerance 19 79.12 Quite High
agonist 10 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 52 92.48 High High
Targeted Disruption 13 88.32 High High
Hyperinsulinism 5 85.44 High High
Impaired Glucose Tolerance 12 78.00 Quite High
Diabetes Mellitus 27 60.16 Quite High
Insulin Resistance 43 51.16 Quite High
Body Weight 6 5.00 Very Low Very Low Very Low
Metabolic Syndrome 5 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Atherosclerosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Adiponectin is an activator of AMP activated protein kinase (AMPK) which is proposed to be a metabolic master switch [29].
Adiponectin Positive_regulation (activator) of AMPK
1) Confidence 0.05 Published 2008 Journal BMC Pharmacol Section Body Doc Link PMC2270815 Disease Relevance 0.94 Pain Relevance 0.12
However, recent observations indicate that activation of AMPK by cytokines, such as adiponectin, involves activation of LKB1 in C2C12 cells (39).
adiponectin Positive_regulation (activation) of AMPK associated with cytokine
2) Confidence 0.03 Published 2008 Journal Diabetes Section Body Doc Link PMC2584126 Disease Relevance 0.14 Pain Relevance 0.05

General Comments

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