INT228180

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 3.58
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ptger2) plasma membrane (Ptger2) signal transducer activity (Ptger2)
Anatomy Link Frequency
lung 2
Ptger2 (Mus musculus)
Pain Link Frequency Relevance Heat
COX-2 inhibitor 6 97.20 Very High Very High Very High
ischemia 38 92.96 High High
metalloproteinase 3 85.00 Quite High
Hippocampus 2 84.32 Quite High
Inflammation 40 77.20 Quite High
fibrosis 3 59.96 Quite High
antagonist 4 58.40 Quite High
Pain 4 50.00 Quite Low
cytokine 6 34.24 Quite Low
Pyramidal cell 2 25.96 Quite Low
Disease Link Frequency Relevance Heat
Hemophilus Infection 89 100.00 Very High Very High Very High
Keloid Scars 50 99.90 Very High Very High Very High
Injury 43 99.30 Very High Very High Very High
Middle Cerebral Artery Infarction 37 99.24 Very High Very High Very High
Burns 5 94.32 High High
Cicatrix 14 93.92 High High
Cv Unclassified Under Development 31 92.96 High High
Hypertrophy 2 84.48 Quite High
Wound Healing 34 79.96 Quite High
INFLAMMATION 50 77.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However 2 hours of MCAO caused a significant increase in the PGE2 concentration of both the contralateral and ipsilateral cPLA2?
Regulation (contralateral) of Localization (concentration) of PGE2 associated with middle cerebral artery infarction
1) Confidence 0.06 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2923122 Disease Relevance 0.54 Pain Relevance 0.22
Furthermore, the pre-treatment of selective COX-2 inhibitor NS398 significantly decreased NTHi-induced PGE2 production to baseline levels, but pre-treatment of selective COX-1 inhibitor SC560 has no effect on NTHi-induced PGE2 release in lung epithelial cells A549.
Neg (no) Regulation (effect) of Localization (release) of PGE2 in lung associated with hemophilus infection and cox-2 inhibitor
2) Confidence 0.02 Published 2008 Journal Respir Res Section Body Doc Link PMC2270828 Disease Relevance 1.10 Pain Relevance 0.05
Mechanical compression of the wound may induce excessive scarring and influence the release of PGE2 and the expression of collagenases.
Spec (may) Regulation (influence) of Localization (release) of PGE2 associated with injury and keloid scars
3) Confidence 0.01 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2910481 Disease Relevance 1.94 Pain Relevance 0.27

General Comments

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