INT228183

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Context Info
Confidence 0.12
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nfkb1) signal transduction (Nfkb1) mitochondrion (Nfkb1)
nucleus (Nfkb1) DNA binding (Nfkb1) nucleic acid binding transcription factor activity (Nfkb1)
Anatomy Link Frequency
myocytes 2
Nfkb1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 2 100.00 Very High Very High Very High
Inflammation 8 20.44 Low Low
Inflammatory mediators 2 15.84 Low Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hemophilus Infection 89 66.24 Quite High
Infection 12 51.12 Quite High
Skin Cancer 1 31.96 Quite Low
INFLAMMATION 12 20.44 Low Low
Sprains And Strains 11 5.00 Very Low Very Low Very Low
Targeted Disruption 10 5.00 Very Low Very Low Very Low
Pulmonary Disease 3 5.00 Very Low Very Low Very Low
Pneumonia 2 5.00 Very Low Very Low Very Low
Bacterial Meningitis 1 5.00 Very Low Very Low Very Low
Bacterial Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, the study by Singer et al. showed that p38 MAPK and NF-kappa B may affect COX-2 expression in human airway myocytes via separate signaling pathways given the fact that SB203580 did not affect cytokine-stimulated IkappaBalpha degradation and NF-kappa B nuclear binding activity [23].
Neg (not) Regulation (affect) of Protein_catabolism (degradation) of NF-kappa B in myocytes associated with cytokine
1) Confidence 0.12 Published 2008 Journal Respir Res Section Body Doc Link PMC2270828 Disease Relevance 0.24 Pain Relevance 0.05

General Comments

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