INT228192

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.96
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Map2k2) kinase activity (Map2k2)
Anatomy Link Frequency
HT-29 1
Map2k2 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 2 63.52 Quite High
Inflammation 8 39.08 Quite Low
Inflammatory mediators 2 34.48 Quite Low
metalloproteinase 7 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Perioperative pain 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 45 90.72 High High
Hemophilus Infection 89 84.88 Quite High
Targeted Disruption 14 75.60 Quite High
Adenocarcinoma 8 67.76 Quite High
Skin Cancer 2 50.60 Quite High
INFLAMMATION 12 39.08 Quite Low
Infection 19 36.92 Quite Low
Cancer 37 5.00 Very Low Very Low Very Low
Sprains And Strains 11 5.00 Very Low Very Low Very Low
Metastasis 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the single inactivation of MEK2 was still capable of abolishing the proliferation of HT-29 cells even in the presence of high MEK1 levels.
Negative_regulation (inactivation) of MEK2 in HT-29
1) Confidence 0.35 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2596176 Disease Relevance 0.50 Pain Relevance 0
Mancuso et al. reported that neither p38 nor ERK MAPK blockade had any effect on Group B streptococci (GBS)-induced NF-kappa B binding activity [21].
Neg (neither) Negative_regulation (blockade) of ERK MAPK
2) Confidence 0.02 Published 2008 Journal Respir Res Section Body Doc Link PMC2270828 Disease Relevance 0.46 Pain Relevance 0.03

General Comments

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