INT22820

Context Info Confidence 0.21 First Reported 1990 Last Reported 1990 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 0 Pain Relevance 0.15

cell proliferation (ADRA1D) peptidase activity (ELANE) extracellular region (ELANE) plasma membrane (ADRA1D) cytoplasm (ELANE) cell-cell signaling (ADRA1D)

Anatomy Link Frequency granulocytes 2 ADRA1D (Homo sapiens) ELANE (Homo sapiens)

Pain Link Frequency Relevance Heat diclofenac 2 100.00 cINOD 2 53.76

Disease Link Frequency Relevance Heat Osteoarthritis 2 5.00 INFLAMMATION 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The effect of diclofenac-Na, glycosaminoglycanpolysulfate (GAGPS), eglin C and alpha 1-proteinase inhibitor on the activity of elastase from polymorphonuclear granulocytes (PMN-elastase) was tested under various conditions.

alpha 1 Regulation (effect) of elastase in granulocytes associated with diclofenac

1) Confidence 0.21 Published 1990 Journal Arzneimittelforschung Section Abstract Doc Link 2334461 Disease Relevance 0 Pain Relevance 0.05

The effect of diclofenac-Na, glycosaminoglycanpolysulfate (GAGPS), eglin C and alpha 1-proteinase inhibitor on the activity of elastase from polymorphonuclear granulocytes (PMN-elastase) was tested under various conditions.

alpha 1 Regulation (effect) of PMN-elastase in granulocytes associated with diclofenac

2) Confidence 0.13 Published 1990 Journal Arzneimittelforschung Section Abstract Doc Link 2334461 Disease Relevance 0 Pain Relevance 0.10

General Comments

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