INT228214

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.97
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Nfkb1, Ptger2) mitochondrion (Nfkb1) DNA binding (Nfkb1)
protein complex (Nfkb1) signal transducer activity (Ptger2) cytoplasm (Nfkb1)
Nfkb1 (Mus musculus)
Ptger2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 8 24.88 Low Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hemophilus Infection 89 99.82 Very High Very High Very High
Bacterial Meningitis 1 64.08 Quite High
Chlamydia Infection 1 62.00 Quite High
Respiratory Syncytial Virus 1 58.08 Quite High
Infection 12 49.28 Quite Low
INFLAMMATION 12 24.88 Low Low
Targeted Disruption 10 9.08 Low Low
Sprains And Strains 11 5.00 Very Low Very Low Very Low
Pulmonary Disease 3 5.00 Very Low Very Low Very Low
Pneumonia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, these data clearly showed that NTHi-induced PGE2 expression is mediated by p38 MAPK- and NF-kappa B-dependent signaling pathway (Fig. 6C).


NF-kappa B-dependent Positive_regulation (mediated) of Gene_expression (expression) of PGE2 associated with hemophilus infection
1) Confidence 0.01 Published 2008 Journal Respir Res Section Body Doc Link PMC2270828 Disease Relevance 0.97 Pain Relevance 0

General Comments

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