INT228216

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.11
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Mapk14, Tlr2) mitochondrion (Mapk14) cell morphogenesis (Mapk14)
intracellular (Tlr2) response to stress (Mapk14) cytosol (Mapk14)
Mapk14 (Mus musculus)
Tlr2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 8 100.00 Very High Very High Very High
cytokine 2 100.00 Very High Very High Very High
Inflammatory mediators 2 97.32 Very High Very High Very High
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 12 100.00 Very High Very High Very High
Infection 12 99.76 Very High Very High Very High
Hemophilus Infection 89 99.32 Very High Very High Very High
Skin Cancer 1 82.88 Quite High
Targeted Disruption 10 75.60 Quite High
Respiratory Syncytial Virus 1 23.60 Low Low
Chlamydia Infection 1 20.92 Low Low
Bacterial Meningitis 1 20.48 Low Low
Sprains And Strains 11 5.00 Very Low Very Low Very Low
Pulmonary Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of p38 MAPK up-regulates inflammatory cytokines, mucin MUC5AC and down-regulates TLR2 expression while activation of NF-kappa B increases the expression of IL-8, IL-1?
Positive_regulation (Activation) of p38 Regulation (regulates) of Gene_expression (expression) of TLR2 associated with inflammation and cytokine
1) Confidence 0.09 Published 2008 Journal Respir Res Section Body Doc Link PMC2270828 Disease Relevance 1.11 Pain Relevance 0.15

General Comments

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