INT228217

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.22
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Nfkb1, Ptger2) mitochondrion (Nfkb1) DNA binding (Nfkb1)
protein complex (Nfkb1) signal transducer activity (Ptger2) cytoplasm (Nfkb1)
Anatomy Link Frequency
PGE2 2
Nfkb1 (Mus musculus)
Ptger2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 8 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hemophilus Infection 89 100.00 Very High Very High Very High
Targeted Disruption 10 98.56 Very High Very High Very High
Pneumonia 2 97.40 Very High Very High Very High
Infection 12 82.40 Quite High
Pulmonary Disease 3 52.36 Quite High
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Sprains And Strains 11 5.00 Very Low Very Low Very Low
Skin Cancer 1 5.00 Very Low Very Low Very Low
Bacterial Meningitis 1 5.00 Very Low Very Low Very Low
Bacterial Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, the role of p38 MAPK and NF-kappa B on the NTHi-induced COX-2 and PGE2 expression was investigated by using their specific chemical inhibitors.


NF-kappa B Spec (investigated) Regulation (role) of Gene_expression (expression) of PGE2 in PGE2 associated with hemophilus infection
1) Confidence 0.01 Published 2008 Journal Respir Res Section Abstract Doc Link PMC2270828 Disease Relevance 1.22 Pain Relevance 0

General Comments

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