INT228298

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Context Info
Confidence 0.65
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 10
Total Number 12
Disease Relevance 6.44
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (INVS) nucleus (INVS) cilium (INVS)
cytoplasm (INVS)
Anatomy Link Frequency
brain 1
INVS (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 28 95.24 Very High Very High Very High
headache 9 79.16 Quite High
cva 73 75.96 Quite High
midbrain 6 56.04 Quite High
imagery 54 47.60 Quite Low
Inflammation 18 9.20 Low Low
cINOD 10 5.00 Very Low Very Low Very Low
COX-2 inhibitor 5 5.00 Very Low Very Low Very Low
fibrosis 5 5.00 Very Low Very Low Very Low
Onset of action 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 487 100.00 Very High Very High Very High
Normal Pressure Hydrocephalus 140 100.00 Very High Very High Very High
Ketoacidosis 60 100.00 Very High Very High Very High
Sprains And Strains 27 99.88 Very High Very High Very High
Brain Disease 6 99.36 Very High Very High Very High
Pressure And Volume Under Development 16 97.12 Very High Very High Very High
Emergencies 12 95.72 Very High Very High Very High
Hydrocephalus 430 94.24 High High
Weight Gain 14 87.40 High High
Arachnoid Cysts 2 86.64 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The Y. pseudotuberculosis invasin protein (inv) is encoded by a 3.8?
Gene_expression (protein) of inv
1) Confidence 0.65 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2938438 Disease Relevance 0.34 Pain Relevance 0
A successful transfer of shRNAs into mammalian cells can be obtained using nonpathogenic E. coli transformed with a plasmid containing an expression cassette for shRNA and Inv/HlyA genes.
Gene_expression (expression) of Inv
2) Confidence 0.37 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2896898 Disease Relevance 0.51 Pain Relevance 0
The Y. pseudotuberculosis invasin protein (inv) is encoded by a 3.8?
Gene_expression (protein) of inv
3) Confidence 0.30 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2938438 Disease Relevance 0.33 Pain Relevance 0
A different approach for bacterial delivery relies on the use of a genetically modified E. coli strains that express two additional genes; inv from Yersinia pseudotuberculosis, and hly from Lysteria monocytogenes [107, 108].
Gene_expression (express) of inv associated with sprains and strains
4) Confidence 0.26 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2938438 Disease Relevance 0.49 Pain Relevance 0
Biphasic insulin aspart versus NPH or glargine in type 2 diabetes
Gene_expression (versus) of NPH associated with diabetes mellitus
5) Confidence 0.11 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350128 Disease Relevance 0.72 Pain Relevance 0
DKA: diabetic ketoacidosis; DM: diabetes mellitus; NPH: neutral protamine Hagedorn; U: units; BE: base excess; Na+: sodium; K+: potassium; CO2: carbon dioxide; pCO2: partial pressure of carbon dioxide; HCO3-: bicarbonate; ?
Gene_expression (ketoacidosis) of NPH associated with diabetes mellitus and ketoacidosis
6) Confidence 0.10 Published 2010 Journal Diabetol Metab Syndr Section Body Doc Link PMC2903515 Disease Relevance 0.96 Pain Relevance 0
Also we understand that NPH is not only a disorder of CSF dynamics, but is also a disorder of the brain.
Gene_expression (dynamics) of NPH in brain associated with normal pressure hydrocephalus and brain disease
7) Confidence 0.07 Published 2008 Journal Cerebrospinal Fluid Res Section Body Doc Link PMC2615740 Disease Relevance 0.77 Pain Relevance 0
NPH is designed to take effect over a much longer period of time,
Gene_expression (take) of NPH
8) Confidence 0.07 Published 2008 Journal International Journal of Telemedicine and Applications Section Body Doc Link PMC2271045 Disease Relevance 0.05 Pain Relevance 0.10
the development of the NPH (neutral protamine hagedorn) insulin, the
Gene_expression (development) of NPH
9) Confidence 0.07 Published 2008 Journal International Journal of Telemedicine and Applications Section Body Doc Link PMC2271045 Disease Relevance 0.58 Pain Relevance 0
NPH is designed to take effect over a much longer period of time,
Gene_expression (designed) of NPH
10) Confidence 0.07 Published 2008 Journal International Journal of Telemedicine and Applications Section Body Doc Link PMC2271045 Disease Relevance 0.05 Pain Relevance 0.10
Domenico d'Avella (on behalf of the Italian NPH group of the SINch, Padova, Italy)
Gene_expression (group) of NPH associated with normal pressure hydrocephalus
11) Confidence 0.06 Published 2008 Journal Cerebrospinal Fluid Res Section Body Doc Link PMC2615740 Disease Relevance 1.42 Pain Relevance 0.24
Trials evaluating insulin glargine versus NPH insulin added to existing OAD therapy have found that treatment with either agent resulted in similar improvements in glycemic control [23,34,35].
Gene_expression (glargine) of NPH
12) Confidence 0.04 Published 2008 Journal Osteopath Med Prim Care Section Body Doc Link PMC2276216 Disease Relevance 0.21 Pain Relevance 0

General Comments

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