INT2283

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Context Info
Confidence 0.32
First Reported 1979
Last Reported 1988
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 7
Disease Relevance 0.68
Pain Relevance 3.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
duodenum 3
blood 1
plasma 1
Apr3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 40 100.00 Very High Very High Very High
anesthesia 2 80.84 Quite High
Disease Link Frequency Relevance Heat
Poisoning 4 96.20 Very High Very High Very High
Body Weight 4 85.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results showed that heavy poisoning with phoschlor led to metabolic disturbances in the proteolytic system of the blood plasma and blood, the expression of which was increasing in the course of time a statistically important increase (alpha = 0,001) of APR-3,5 and APR-7,4.
Positive_regulation (increase) of APR-3 in blood associated with poisoning
1) Confidence 0.32 Published 1979 Journal Pol Arch Weter Section Abstract Doc Link 400184 Disease Relevance 0.34 Pain Relevance 0.08
The results showed that heavy poisoning with phoschlor led to metabolic disturbances in the proteolytic system of the blood plasma and blood, the expression of which was increasing in the course of time a statistically important increase (alpha = 0,001) of APR-3,5 and APR-7,4.
Positive_regulation (increase) of APR-3 in plasma associated with poisoning
2) Confidence 0.11 Published 1979 Journal Pol Arch Weter Section Abstract Doc Link 400184 Disease Relevance 0.34 Pain Relevance 0.08
Doses of morphine effective in inducing premature Phase III-like activity led to increases in plasma motilin concentration that occurred only after Phase III-like activity had begun in the duodenum.
Positive_regulation (inducing) of Phase III-like in duodenum associated with morphine
3) Confidence 0.00 Published 1988 Journal Surgery Section Abstract Doc Link 3375992 Disease Relevance 0 Pain Relevance 0.62
Both motilin and morphine induced premature Phase III-like activity in the duodenum, the characteristics of which were similar to those of spontaneous Phase III except that the velocity of migration in morphine-induced Phase III-like activity was greater.
Positive_regulation (induced) of Phase III-like in duodenum associated with morphine
4) Confidence 0.00 Published 1988 Journal Surgery Section Abstract Doc Link 3375992 Disease Relevance 0 Pain Relevance 0.59
The minimum effective doses of motilin and morphine necessary to induce premature Phase III-like activity when given intravenously were also determined.
Positive_regulation (induce) of Phase III-like associated with morphine
5) Confidence 0.00 Published 1988 Journal Surgery Section Abstract Doc Link 3375992 Disease Relevance 0 Pain Relevance 0.57
Both motilin and morphine induced premature Phase III-like activity in the duodenum, the characteristics of which were similar to those of spontaneous Phase III except that the velocity of migration in morphine-induced Phase III-like activity was greater.
Neg (except) Positive_regulation (morphine-induced) of Phase III-like in duodenum associated with morphine
6) Confidence 0.00 Published 1988 Journal Surgery Section Abstract Doc Link 3375992 Disease Relevance 0 Pain Relevance 0.64
Site of action of morphine sulfate and motilin in the induction of "premature" phase III-like activity in the canine gastrointestinal tract.
Positive_regulation (induction) of phase III-like associated with morphine
7) Confidence 0.00 Published 1988 Journal Surgery Section Title Doc Link 3375992 Disease Relevance 0 Pain Relevance 0.47

General Comments

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