INT228437

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.08
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mtpn) nucleus (Mtpn) cytoplasm (Mtpn)
Mtpn (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antidepressant 111 100.00 Very High Very High Very High
Endep 9 96.60 Very High Very High Very High
fluoxetine 12 93.32 High High
Hippocampus 12 87.20 High High
depression 15 40.52 Quite Low
Neurotransmitter 6 18.28 Low Low
Catecholamine 9 11.12 Low Low
Dopamine 3 5.00 Very Low Very Low Very Low
Serotonin 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 21 77.56 Quite High
Clinical Trials And Case Reports 3 42.08 Quite Low
Stress 3 6.96 Low Low
Affective Disorder 3 5.00 Very Low Very Low Very Low
Toxicity 3 5.00 Very Low Very Low Very Low
Suicidal Behaviour 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of magnetic stimulation and antidepressants on different growth factor transcription were analysed by rtPCR and were summarized in figure 2.
Regulation (effects) of Transcription (transcription) of growth factor associated with antidepressant
1) Confidence 0.03 Published 2008 Journal BMC Pharmacol Section Body Doc Link PMC2275236 Disease Relevance 0.08 Pain Relevance 0.36
The general common observation was that all four antidepressant drugs counteracted alterations of growth factor transcription, induced by PMA.
Regulation (alterations) of Transcription (transcription) of growth factor associated with antidepressant
2) Confidence 0.01 Published 2008 Journal BMC Pharmacol Section Body Doc Link PMC2275236 Disease Relevance 0 Pain Relevance 0.32
We conclude from our experiments that antidepressant drugs rather modulate PMA-induced changes of growth factor transcription, than induce an overall transcription increase.
Regulation (modulate) of Transcription (transcription) of growth factor associated with antidepressant
3) Confidence 0.01 Published 2008 Journal BMC Pharmacol Section Body Doc Link PMC2275236 Disease Relevance 0 Pain Relevance 0.34

General Comments

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