INT228454

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Context Info
Confidence 0.39
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.97
Pain Relevance 2.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Trpv1) transmembrane transport (Trpv1) lipid metabolic process (Trpv1)
cytosol (Trpv1) extracellular space (Ngf) signal transduction (Ngf)
Anatomy Link Frequency
nerve 4
Ngf (Mus musculus)
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
Serotonin 2 100.00 Very High Very High Very High
Nerve growth factor 2 100.00 Very High Very High Very High
Glutamate 2 100.00 Very High Very High Very High
bradykinin 2 100.00 Very High Very High Very High
Inflammation 4 96.96 Very High Very High Very High
Dopamine 6 96.44 Very High Very High Very High
c fibre 2 89.64 High High
unmyelinated 2 89.28 High High
diabetic neuropathy 34 89.04 High High
qutenza 20 87.60 High High
Disease Link Frequency Relevance Heat
INFLAMMATION 4 96.96 Very High Very High Very High
Peripheral Neuropathy 34 89.04 High High
Diabetes Mellitus 236 80.88 Quite High
Neuropathic Pain 16 79.92 Quite High
Rodent Diseases 2 66.84 Quite High
Hyperglycemia 16 65.92 Quite High
Hyperalgesia 96 65.00 Quite High
Impaired Glucose Tolerance 2 60.96 Quite High
Hypoalagesia 28 60.08 Quite High
Pain 42 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sensitization of TRPV1 by phosphorylation is mediated by numerous factors including, prostaglandins [17,18], bradykinin [19-21], glutamate [22], serotonin [23], histamine [24], ATP [25-27], trypsin [28,29] and nerve growth factor (NGF) [14,30].
NGF Positive_regulation (mediated) of Phosphorylation (phosphorylation) of TRPV1 in nerve associated with glutamate, nerve growth factor, serotonin and bradykinin
1) Confidence 0.39 Published 2008 Journal Mol Pain Section Body Doc Link PMC2275252 Disease Relevance 1.49 Pain Relevance 1.13
Sensitization of TRPV1 by phosphorylation is mediated by numerous factors including, prostaglandins [17,18], bradykinin [19-21], glutamate [22], serotonin [23], histamine [24], ATP [25-27], trypsin [28,29] and nerve growth factor (NGF) [14,30].
nerve growth factor Positive_regulation (mediated) of Phosphorylation (phosphorylation) of TRPV1 in nerve associated with glutamate, nerve growth factor, serotonin and bradykinin
2) Confidence 0.39 Published 2008 Journal Mol Pain Section Body Doc Link PMC2275252 Disease Relevance 1.48 Pain Relevance 1.13

General Comments

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