INT228617

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Context Info
Confidence 0.69
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.56
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (EXT2) signal transduction (EXT2) transferase activity, transferring glycosyl groups (EXT2)
Golgi apparatus (EXT2) endoplasmic reticulum (EXT2)
Anatomy Link Frequency
limb buds 1
EXT2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 20 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
positron emission tomography 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteochondroma 94 90.00 High High
Multiple Hereditary Exostoses 90 84.84 Quite High
Chondrosarcoma 28 81.52 Quite High
Cancer 16 77.24 Quite High
Cleidocranial Dysplasia 6 70.68 Quite High
Malignant Neoplastic Disease 32 5.00 Very Low Very Low Very Low
Pain 20 5.00 Very Low Very Low Very Low
Congenital Anomalies 10 5.00 Very Low Very Low Very Low
Enchondromatosis 8 5.00 Very Low Very Low Very Low
Bone Cancer 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both EXT1 and EXT2 mRNA is ubiquitously expressed [17-19].
Transcription (expressed) of EXT2
1) Confidence 0.69 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2276198 Disease Relevance 0.79 Pain Relevance 0
A high level of expression of Ext1 and Ext2 mRNA has been found in developing limb buds of mouse embryos [44,45] and expression was demonstrated to be confined to the proliferating and prehypertrophic chondrocytes of the growth plate [46].
Transcription (expression) of Ext2 in limb buds
2) Confidence 0.52 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2276198 Disease Relevance 0.78 Pain Relevance 0

General Comments

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