INT228620

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Context Info
Confidence 0.71
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.67
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (EXT1) transferase activity, transferring glycosyl groups (EXT1) Golgi apparatus (EXT1)
endoplasmic reticulum (EXT1)
Anatomy Link Frequency
nodule 1
limb buds 1
EXT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 20 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
positron emission tomography 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Immunotherapy Of Cancer 1 99.88 Very High Very High Very High
Cancer 94 99.04 Very High Very High Very High
Osteochondroma 94 90.36 High High
Multiple Hereditary Exostoses 90 85.20 High High
Chondrosarcoma 28 80.80 Quite High
Liver Disease 13 75.72 Quite High
Infection 4 74.96 Quite High
Hepatitis C Virus Infection 4 74.56 Quite High
Hepatitis B Virus Infection 3 72.72 Quite High
Cleidocranial Dysplasia 6 71.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both EXT1 and EXT2 mRNA is ubiquitously expressed [17-19].
Transcription (expressed) of EXT1
1) Confidence 0.71 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2276198 Disease Relevance 0.79 Pain Relevance 0
A high level of expression of Ext1 and Ext2 mRNA has been found in developing limb buds of mouse embryos [44,45] and expression was demonstrated to be confined to the proliferating and prehypertrophic chondrocytes of the growth plate [46].
Transcription (expression) of Ext1 in limb buds
2) Confidence 0.53 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2276198 Disease Relevance 0.77 Pain Relevance 0
Distribution and association of TTV and number and size of tumor nodule
Transcription (Distribution) of TTV in nodule associated with cancer
3) Confidence 0.37 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC3022616 Disease Relevance 1.11 Pain Relevance 0

General Comments

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