INT228681

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.57
Pain Relevance 1.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Fkbp4, Trib3) nucleus (Fkbp4, Trib3) isomerase activity (Fkbp4)
enzyme binding (Trib3) protein complex (Fkbp4) cytoplasm (Fkbp4)
Fkbp4 (Rattus norvegicus)
Trib3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 39 92.24 High High
Hyperalgesia 28 91.32 High High
withdrawal 14 71.96 Quite High
nociceptor 41 70.24 Quite High
central sensitization 4 8.44 Low Low
Calcitonin gene-related peptide 9 5.00 Very Low Very Low Very Low
Pain 8 5.00 Very Low Very Low Very Low
Sciatic nerve 5 5.00 Very Low Very Low Very Low
Lasting pain 4 5.00 Very Low Very Low Very Low
Dorsal horn 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperalgesia 31 91.32 High High
Pain 13 5.00 Very Low Very Low Very Low
Injury 10 5.00 Very Low Very Low Very Low
Nervous System Injury 8 5.00 Very Low Very Low Very Low
Nociception 6 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Neuropathic Pain 3 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Camurati-engelmann Disease 2 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been shown that rapamycin forms a complex with the immunophilin FK506-binding protein 12 (FKBP12), which then inhibits the protein kinase activity of mTOR.
immunophilin FK506-binding Negative_regulation (inhibits) of kinase
1) Confidence 0.00 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2276314 Disease Relevance 0.57 Pain Relevance 1.20

General Comments

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