INT228685

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Context Info
Confidence 0.26
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.64
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (SCD) endoplasmic reticulum (SCD)
Anatomy Link Frequency
liver 2
SCD (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 65 100.00 Very High Very High Very High
Pain 17 84.64 Quite High
Lasting pain 1 44.72 Quite Low
tolerance 1 41.04 Quite Low
biopsychosocial 2 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Pain management 1 5.00 Very Low Very Low Very Low
qutenza 1 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 67 100.00 Very High Very High Very High
Sickle Cell Anemia 62 100.00 Very High Very High Very High
Fatty Liver 1 98.00 Very High Very High Very High
Targeted Disruption 1 96.04 Very High Very High Very High
Obesity 7 89.88 High High
Disease 21 89.48 High High
Stress 2 68.64 Quite High
Death 2 61.88 Quite High
Pain 9 44.72 Quite Low
Anxiety Disorder 3 42.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Depression, loneliness and SCD
Negative_regulation (loneliness) of Gene_expression (Depression) of SCD associated with sickle cell anemia and depression
1) Confidence 0.26 Published 2010 Journal BMC Psychiatry Section Body Doc Link PMC2894759 Disease Relevance 1.29 Pain Relevance 0.38
In a more mechanistic fashion, recent studies have also suggested EGCG may alter food digestibility [15,36] and downregulate stearoyl-CoA desaturase (SCD1) gene expression [15], which may reduce adiposity, decrease lipid synthesis and increase liver fatty acid oxidation, as was found in SCD1 knockout mice [15,37].
Negative_regulation (reduce) of Gene_expression (expression) of desaturase in liver associated with targeted disruption and fatty liver
2) Confidence 0.04 Published 2008 Journal J Int Soc Sports Nutr Section Body Doc Link PMC2276475 Disease Relevance 0.36 Pain Relevance 0

General Comments

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