INT228720

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Context Info
Confidence 0.32
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.64
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
B cells 1
Cd69 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 1 80.80 Quite High
Multiple sclerosis 48 61.36 Quite High
Inflammation 71 55.04 Quite High
cytokine 76 51.60 Quite High
chemokine 19 40.24 Quite Low
rheumatoid arthritis 88 5.00 Very Low Very Low Very Low
psoriasis 44 5.00 Very Low Very Low Very Low
Arthritis 26 5.00 Very Low Very Low Very Low
Adalimumab 9 5.00 Very Low Very Low Very Low
Etanercept 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibromyalgia 1 98.84 Very High Very High Very High
Asthma 40 96.12 Very High Very High Very High
Disease 77 84.08 Quite High
Multiple Sclerosis 57 61.36 Quite High
Apoptosis 11 58.48 Quite High
INFLAMMATION 72 55.04 Quite High
Autoimmune Disease 33 50.00 Quite Low
Eosinophilia 2 50.00 Quite Low
Lymphatic System Cancer 2 47.28 Quite Low
Death 10 45.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
T cells were accompanied by concurrent decreases in absolute number of CD3+/CD69+, IgE+/B220+ B cells (Table 2, Figure 6).
Negative_regulation (decreases) of CD69 in B cells
1) Confidence 0.32 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2276601 Disease Relevance 0.28 Pain Relevance 0.05
These genes included downregulation for CD69, c-jun, c-fos, flt3 ligand (fms-like tyrosine kinase 3 gene), I?
Negative_regulation (downregulation) of CD69 associated with fibromyalgia
2) Confidence 0.19 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2768824 Disease Relevance 0.36 Pain Relevance 0.10

General Comments

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