INT228742

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Context Info
Confidence 0.14
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.88
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Ccr3) signal transduction (Ccr3) extracellular space (Ccr3)
plasma membrane (Ccr3) nucleus (Rae1) signal transducer activity (Ccr3)
Anatomy Link Frequency
eosinophil 2
Rae1 (Mus musculus)
Ccr3 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 46 90.64 High High
Inflammation 54 62.20 Quite High
chemokine 4 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 80 85.48 High High
Eczema 2 84.64 Quite High
Hypersensitivity 20 83.08 Quite High
Disease 16 67.20 Quite High
Adhesions 6 62.76 Quite High
INFLAMMATION 54 62.20 Quite High
Eosinophilia 4 50.00 Quite Low
Rhinitis 14 5.00 Very Low Very Low Very Low
Occupational Lung Diseases 4 5.00 Very Low Very Low Very Low
Pneumonia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results indicate that RAE could decrease CCR3 expression of BALF cells

(especially eosinophils), data of which are compatible with airway eosinophil

RAE Negative_regulation (decrease) of Gene_expression (expression) of CCR3 in eosinophil
1) Confidence 0.14 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2276601 Disease Relevance 0.57 Pain Relevance 0.06
Our results show that RAE and CsA downregulate CCR3 expression and CD4+CD8?
RAE Negative_regulation (downregulate) of Gene_expression (expression) of CCR3
2) Confidence 0.14 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2276601 Disease Relevance 0.31 Pain Relevance 0.05

General Comments

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