INT228759

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.32
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il5) extracellular region (Il5) nucleus (Rae1)
cytoplasm (Rae1)
Anatomy Link Frequency
lung 1
eosinophils 1
T cells 1
Rae1 (Mus musculus)
Il5 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 69 99.52 Very High Very High Very High
chemokine 6 9.44 Low Low
Inflammation 81 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 24 99.12 Very High Very High Very High
Hypersensitivity 30 98.76 Very High Very High Very High
Asthma 120 98.24 Very High Very High Very High
Adhesions 9 82.72 Quite High
Eosinophilia 6 50.00 Quite Low
Increased Venous Pressure Under Development 3 10.36 Low Low
Eczema 3 9.44 Low Low
INFLAMMATION 81 5.00 Very Low Very Low Very Low
Rhinitis 21 5.00 Very Low Very Low Very Low
Occupational Lung Diseases 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As you see Table 1, RAE decreased IL-4, IL-5, and IL-13 cytokines, It has been suggested that RAE may be has suppressing activities of CD4+ T cells, eosinophils inducing asthmatic inflammations.
RAE Negative_regulation (decreased) of IL-5 in eosinophils associated with asthma and cytokine
1) Confidence 0.09 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2276601 Disease Relevance 0.16 Pain Relevance 0.13
In

our study, RAE significantly reduced IL-5 levels in BALF (Figure 7) as well as mRNA expression of IL-13 in lung (Table 3).

RAE Negative_regulation (reduced) of IL-5 in lung
2) Confidence 0.08 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2276601 Disease Relevance 1.00 Pain Relevance 0.08
As you see Table 1, RAE decreased IL-4, IL-5, and IL-13 cytokines, It has been suggested that RAE may be has suppressing activities of CD4+ T cells, eosinophils inducing asthmatic inflammations.
RAE Negative_regulation (decreased) of IL-5 in T cells associated with asthma and cytokine
3) Confidence 0.03 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2276601 Disease Relevance 0.16 Pain Relevance 0.13

General Comments

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