INT228839

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Mtf2) DNA binding (Mtf2) cytoplasm (Mtf2)
Anatomy Link Frequency
dopaminergic neurons 1
Mtf2 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 96 98.60 Very High Very High Very High
dopamine receptor 12 95.52 Very High Very High Very High
Ventral tegmentum 24 95.44 Very High Very High Very High
amygdala 2 71.28 Quite High
Nucleus accumbens 38 69.92 Quite High
Substantia nigra 2 44.00 Quite Low
cocaine 10 5.00 Very Low Very Low Very Low
Eae 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Attention Deficit Hyperactivity Disorder 10 11.04 Low Low
Sprains And Strains 8 5.00 Very Low Very Low Very Low
Aggression 6 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Anxiety Disorder 4 5.00 Very Low Very Low Very Low
Manic Depressive Disorder 4 5.00 Very Low Very Low Very Low
Depression 4 5.00 Very Low Very Low Very Low
Birth Weight 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, no difference in TH-ir area was observed within any of these regions, including ZI (Fig. 6C, p>0.05, N?
Gene_expression (observed) of ZI
1) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2276864 Disease Relevance 0 Pain Relevance 0.27
Although TH is also involved in norepinephrine (NE) synthesis, ZI contains a high number of dopaminergic neurons [51], [52] and the dopamine beta hydroxylase enzyme necessary for NE production has little or no expression in ZI, so pTH activity there is thought to reflect dopamine synthesis.
Gene_expression (expression) of ZI in dopaminergic neurons associated with dopamine
2) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2276864 Disease Relevance 0 Pain Relevance 0.40

General Comments

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