INT228903

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Context Info
Confidence 0.42
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
uterine 2
PHOSPHO1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 69 98.44 Very High Very High Very High
Metastasis 2 88.04 High High
Leiomyosarcoma 18 76.08 Quite High
Epithelioid Leiomyoma 4 74.76 Quite High
Smooth Muscle Tumor 14 67.44 Quite High
Uterine Fibroids 7 61.32 Quite High
Uterine Cancer 3 59.56 Quite High
Tuberous Sclerosis 2 53.08 Quite High
Gastrointestinal Stromal Tumor 1 37.84 Quite Low
Muscle Neoplasms 5 12.80 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The recent demonstration of elevated phospho-p70S6K and reduced phospho-AKT expression, indicative of mTOR (mammalian target of rapamycin) activation, in a group of extra-renal PEComas raises the possibility of using mTOR inhibitors such as rapamycin in the treatment of uterine PEComas and is another argument for their routine segregation [82].
Negative_regulation (reduced) of Gene_expression (expression) of phospho in uterine
1) Confidence 0.42 Published 2008 Journal Int Semin Surg Oncol Section Body Doc Link PMC2278149 Disease Relevance 0.79 Pain Relevance 0

General Comments

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